1-苯基-1H-吡唑-5-甲醛合成路线 （共 2 条）
反应条件
1: 1-phenyl-1H-pyrazole With n-butyllithium in tetrahydrofuran; n-heptane T=-78°C; 2 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; n-heptane T=-78 - 20°C; 19 h; Further stages.;
参考文献
Schlaeger, Torsten; Schepmann, Dirk; Lehmkuhl, Kirstin; Holenz, Joerg; Vela, Jose Miguel; Buschmann, Helmut; Wuensch, Bernhard
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6704 - 6713
反应条件
toluene-4-sulfonic acid in methanol T=20°C; 20 h;
参考文献
Schlaeger, Torsten; Schepmann, Dirk; Wuerthwein, Ernst-Ulrich; Wuensch, Bernhard
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 6 p. 2992 - 3001
