4-氨基-3-疏基-5-(2-氯苯基)-[1,2,4-]噻唑合成路线 （共 6 条）
反应条件
1: With potassium hydroxide in ethanol T=20°C; 12 h; 2: With hydrazine hydrate in water 6 h; Reflux; 3: With hydrogenchloride in water Cooling;
参考文献
Cheeseright, Timothy J.; Holm, Melanie; Lehmann, Frank; Luik, Sabine; Gottert, Marcia; Melville, James L.; Laufer, Stefan
Journal of Medicinal Chemistry, 2009 , vol. 52, # 14 p. 4200 - 4209
反应条件
hydrazine hydrate 0.133333 h; microwave irradiation;
参考文献
Joshi; Karnik
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 4 p. 1057 - 1059
反应条件
hydrazine hydrate 3 h; Heating;
参考文献
Joshi; Karnik
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 4 p. 1057 - 1059
反应条件
1.1: H2NNH2*H2O 2.1: KOH 2.2: H2NNH2*H2O / 120 °C View Scheme
参考文献
Li, Dejiang; Long, Deqing; Fu, Heqing
Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 9 p. 2079 - 2087
反应条件
1.1: H2SO4 2.1: H2NNH2*H2O 3.1: KOH 3.2: H2NNH2*H2O / 120 °C View Scheme
参考文献
Li, Dejiang; Long, Deqing; Fu, Heqing
Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 9 p. 2079 - 2087
参考文献
Chandra, Trilok; Garg, Neha; Kumar, Ashok
Pakistan Journal of Scientific and Industrial Research, 2009 , vol. 52, # 5 p. 243 - 252
