1: N-methyl-N-phenylmethanesulfonamide With n-butyllithium in tetrahydrofuran T=-30°C; 2: carbonic acid diethyl ester in tetrahydrofuran T=-30 - 20°C;

1: N-methyl-N-phenylmethanesulfonamide With zinc(II) chloride; lithium hexamethyldisilazane in tetrahydrofuran T=-20 - 20°C; 1 h; Inert atmosphere; 2: bromobenzene With palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in tetrahydrofuran T=20 - 65°C; Negishi coupling reaction; Inert atmosphere;

triphenylphosphine; sodium t-butanolate; palladium diacetate in toluene T=100 - 110°C;