1: 90 percent / LS-Selectride / tetrahydrofuran / 0.17 h / -78 °C 2: 84 percent / 8 h / 57 °C 3: 51 percent / K2CO3, 18-crown-6 / dimethylformamide / 21 h / 110 °C 4: 1.) NaOMe, 2.) 3N HCl / 1.) MeOH, 40 deg C, 2 h, 2.) 50 deg C, 2 h View Scheme

LS-Selectridereg; in tetrahydrofuran T=-78°C; 0.166667 h;

in acetone 4 h; Irradiationother cyclobutanones; var. solvents, times, and conditions; Product distribution;