Fmoc-N-三苯甲基-L-谷氨酰胺合成路线 （共 17 条）
反应条件
sulfuric acid; acetic anhydride in water; acetic acid
反应条件
1: 35 percent / Ac2O, conc.H2SO4 / acetic acid / 60 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742
反应条件
1: 67 percent / Ac2O, conc.H2SO4 / acetic acid / 1 h / 50 °C 2: 93 percent / H2, 1N HCl / 10percent Pd-C / methanol; H2O / 1 h View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742
反应条件
1: 93 percent / H2, 1N HCl / 10percent Pd-C / methanol; H2O / 1 h View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742
反应条件
1: 35 percent / Ac2O, conc.H2SO4 / acetic acid / 60 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742
参考文献
Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742
反应条件
1.1: i-BuOCOCl; NMM / tetrahydrofuran / 0.33 h / -16 °C 1.2: 50.3 percent / tetrahydrofuran; CH2Cl2 / 1.5 h 2.1: 42 percent / AgOBz / dioxane; H2O / 20 °C / sonication View Scheme
参考文献
Gelman, Michael A.; Richter, Sara; Cao, Hong; Umezawa, Naoki; Gellman, Samuel H.; Rana, Tariq M.
Organic Letters, 2003 , vol. 5, # 20 p. 3563 - 3565
反应条件
hydrogenchloride in water T=20°C; 0.25 h;
参考文献
Organic Letters, , vol. 14, # 24 p. 6346 - 6349
反应条件
1: N-(9-fluorenylmethoxycarbonyl)glycine With ethyl (hydroxylimino)cyanoacetate; diisopropyl-carbodiimide in N,N-dimethyl-formamide T=20°C; 1 h; 2: With piperidine in N,N-dimethyl-formamide 3: N-Fmoc-L-leucine; C27H27NO7S2; Fmoc–Pro–OH; fmoc-L-Ile-OH; fmoc-O-tert-butyl-L-tyrosine; fmoc-Asn(trt)-OH; fmoc-Gln(Trt)-OH Further stages;
参考文献
Postma, Tobias M.; Albericio, Fernando
Organic Letters, 2013 , vol. 15, # 3 p. 616 - 619
反应条件
sodium azide in N,N-dimethyl-formamide T=50°C; 9 h;
参考文献
Chen, Chun-Chi; Rajagopal, Basker; Liu, Xuan Yu; Chen, Kuan Lin; Tyan, Yu-Chang; Lin, Fui; Lin, Po-Chiao
Amino Acids, 2014 , vol. 46, # 2 p. 367 - 374
