S-(+)-N,N-二甲基-3-(1-萘氧基)-3-(2-噻吩)-丙胺合成路线 (共 21 条)
反应条件
1: With N-ethyl-N,N-diisopropylamine; phenyl chloroformate in toluene T=60 - 80°C; 2 h; 2: With potassium hydroxide in ethanol; water 2 h; Heating / reflux; 3: With ammonium chloride in ethanol 2 h; Heating / reflux;
参考文献
ZENTIVA, K.S.; RIDVAN, Ludek; CINIBULK, Josef; GRUNWALDOVA, Veronika; BRUSOVA, Hana
Patent: WO2011/26449 A1, 2011 ;
Location in patent: Page/Page column 9 ;