1.1: sodium hydroxide / methanol / 0.5 h / Reflux 2.1: triethylamine; p-toluenesulfonyl chloride / benzene / Inert atmosphere; Reflux 3.1: bis(dibenzylideneacetone)-palladium(0); Pd0(tris(tert-butyl)phosphine)2 / toluene / 2 h / 100 °C / Inert atmosphere 4.1: hydrogenchloride; water / toluene; diethyl ether 4.2: pH 10 View Scheme

1.1: sodium hydroxide / methanol / 0.5 h / Reflux 2.1: triethylamine; p-toluenesulfonyl chloride / benzene / Inert atmosphere; Reflux 3.1: bis(dibenzylideneacetone)-palladium(0); Pd0(tris(tert-butyl)phosphine)2 / toluene / 2 h / 100 °C / Inert atmosphere 4.1: hydrogenchloride; water / toluene; diethyl ether 4.2: pH 10 5.1: triethylamine / dichloromethane / 0.5 h / 10 °C / Inert atmosphere 6.1: AlCl3, aluminium chloride / dichloromethane / 0 - 10 °C 7.1: sodium hydroxide / tetrahydrofuran / 3 h / 20 °C View Scheme

1: sodium hydroxide / methanol / 0.5 h / Reflux 2: triethylamine; p-toluenesulfonyl chloride / benzene / Inert atmosphere; Reflux View Scheme