2,3,4,6-四-O-乙酰基-1-溴-Alpha-D-甘露糖合成路线 （共 50 条）
反应条件
1: 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl bromide With N,N-dimethylimidazolone; ethylene glycol dimethyl ether; nickel dichloride T=20°C; 0.333333 h; 2: bromo(4-ethoxy-4-oxobutyl)zinc 12 h; Title compound not separated from byproducts;
参考文献
Gong, Hegui; Sinisi, Riccardo; Gagne, Michel R.
Journal of the American Chemical Society, 2007 , vol. 129, # 7 p. 1908 - 1909
反应条件
1: 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl bromide With N,N-dimethylimidazolone; ethylene glycol dimethyl ether; nickel dichloride T=20°C; 0.333333 h; 2: (2-(1,3-dioxolan-2-yl)ethyl)zinc(II) bromide 12 h; Title compound not separated from byproducts;
参考文献
Gong, Hegui; Sinisi, Riccardo; Gagne, Michel R.
Journal of the American Chemical Society, 2007 , vol. 129, # 7 p. 1908 - 1909
反应条件
2,6-dimethylpyridine in dichloromethane 4 h;
参考文献
Lam, Son N.; Gervay-Hague, Jacquelyn
Journal of Organic Chemistry, 2005 , vol. 70, # 6 p. 2387 - 2390
反应条件
ethanol; silver carbonate
参考文献
Levene; Sobotka
Journal of Biological Chemistry, 1926 , vol. 67, p. 771,775
反应条件
1: 81 percent / 4 Angstroem molecular sieves, silver triflate / CH2Cl2; toluene / 0.67 h / -40 °C 2: HOAc, H2 / Pd-C / ethanol 3: 79 percent / NaOMe / Ambient temperature View Scheme
参考文献
Winnik; Brisson; Carver; Krepinsky
Carbohydrate research, 1982 , vol. 103, # 1 p. 15 - 28
反应条件
1: 67 percent / mercuric bromide, mercuric cyanide, 4A molecular sieves / acetonitrile / 1 h / Ambient temperature 2: 1.) acetic acid, sodium acetate; 2.) methanol / 1.) 10 percent palladium-on-charcoal; 2.) 2 M sodium methoxide / 1.) ethanol, water, heating for 17 h at 75 deg C; 2.) 30 min View Scheme
参考文献
Winnik; Brisson; Carver; Krepinsky
Carbohydrate research, 1982 , vol. 103, # 1 p. 15 - 28
反应条件
tetrabutylammomium bromide; sodium acetate in acetonitrile T=20°C; 3 h; Molecular sieveultrasound irradiation;
参考文献
Zhao, Jinzhong; Wei, Shanqiao; Yue, Aiqin; Shao, Huawu
Chinese Journal of Chemistry, 2012 , vol. 30, # 3 p. 627 - 633
反应条件
tetrabutylammomium bromide in dichloromethane Condensation; 21 h; Heating;
参考文献
Baeschlin, Daniel K.; Green, Luke G.; Hahn, Michael G.; Hinzen, Berthold; Ince, Stuart J.; Ley, Steven V.
Tetrahedron Asymmetry, 2000 , vol. 11, # 1 p. 173 - 197
反应条件
silver trifluoromethanesulfonate in dichloromethane T=0°C;
参考文献
Nobrega, Chaxiraxi; Vazquez, Jesus T.
Tetrahedron Asymmetry, 2003 , vol. 14, # 18 p. 2793 - 2801
参考文献
Isbell; Frush
Journal of Research of the National Bureau of Standards (United States), 1949 , vol. 43, p. 161,165, 166
