1: 62 percent / Ph3P, CCl4 / 15 h / Heating 2: Li, 1percent Na / tetrahydrofuran / 2 h / Irradiation View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 70 percent / tetrahydrofuran / 0.5 h / Ambient temperature<br />2: 1.) n-BuLi, TMEDA / 1.) hexane, -78 deg C, 15 min, 2.) a) -78 deg C, 30 min, b) 0 deg C, 15 min, c) RT, 30 min<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1209227', constants.ctx, '0')">n-butyllithium</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1732991', constants.ctx, '0')">N,N,N',N,-tetramethylethylenediamine</a> <br />&nbsp;1.) hexane, -78 deg C, 15 min, 2.) a) -78 deg C, 30 min, b) 0 deg C, 15 min, c) RT, 30 min;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;