1: cyclopentanone With pyrrolidine; toluene-4-sulfonic acid in benzene 3 h; Heating; 2: 1-bromo-2-(bromomethyl)benzene in benzene Heating; 3: With water; sodium acetate; acetic acid in benzene 1 h; Heating; Further stages.;
参考文献
Hoegenauer, Klemens; Mulzer, Johann
Organic Letters, 2001 , vol. 3, # 10 p. 1495 - 1497
1: dioxane / 8 h / Heating 2: water / 2 h / Heating View Scheme
参考文献
Hays, Sheryl J.; Novak, Perry M.; Ortwine, Daniel F.; Bigge, Christopher F.; Colbry, Norman L.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 6 p. 654 - 670