N-甲基-6-硝基-1,3-苯并噻唑-2-胺合成路线 （共 7 条）
反应条件
in tetrahydrofuran; water
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/66173 A2, 2006 ;
Location in patent: Page/Page column 84 ;
WO 2006/066173 A2
反应条件
bromine in acetic acid 1 h; Ambient temperature;
参考文献
Ambati, Narahari Babu; Anand; Hanumanthu
Synthetic Communications, 1997 , vol. 27, # 9 p. 1487 - 1493
反应条件
in toluene T=110°C; 96 h;
参考文献
L'abbe, Garrit; Buelens, Karin
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 1993 - 1995
反应条件
1: 75 percent / methanol / 1 h / Heating 2: 45 percent / Br2 / acetic acid / 1 h / Ambient temperature View Scheme
参考文献
Ambati, Narahari Babu; Anand; Hanumanthu
Synthetic Communications, 1997 , vol. 27, # 9 p. 1487 - 1493
反应条件
1: 83 percent / NaN3 / ethanol; acetone / 0 °C 2: 28 percent / diethyl ether; H2O; methanol / 24 h 3: 39 percent / toluene / 96 h / 110 °C View Scheme
参考文献
L'abbe, Garrit; Buelens, Karin
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 1993 - 1995
反应条件
1: 28 percent / diethyl ether; H2O; methanol / 24 h 2: 39 percent / toluene / 96 h / 110 °C View Scheme
参考文献
L'abbe, Garrit; Buelens, Karin
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 1993 - 1995
参考文献
Hunter; Jones
Journal of the Chemical Society, 1930 , p. 2190,2209
