1-N-boc-4(r)-氨基-吡咯烷-2(r)-羧酸合成路线 （共 6 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol; water P=5171.5 Torr;
参考文献
Webb, Thomas R.; Eigenbrot, Charles
Journal of Organic Chemistry, 1991 , vol. 56, # 9 p. 3009 - 3016
反应条件
1: 94 percent / N,N-diisopropylethylamine / dioxane 2: 74 percent / CBr4, PPh3 / CH2Cl2 / 18 h 3: NaN3 / dimethylformamide / 55 °C 4: 83 percent / H2 / 10percent Pd/C / H2O; ethanol / 5171.5 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 9 p. 3009 - 3016
反应条件
1: NaN3 / dimethylformamide / 55 °C 2: 83 percent / H2 / 10percent Pd/C / H2O; ethanol / 5171.5 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 9 p. 3009 - 3016
反应条件
1: 94 percent / N,N-diisopropylethylamine / dioxane 2: 74 percent / CBr4, PPh3 / CH2Cl2 / 18 h 3: NaN3 / dimethylformamide / 55 °C 4: 83 percent / H2 / 10percent Pd/C / H2O; ethanol / 5171.5 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 9 p. 3009 - 3016
反应条件
1: 74 percent / CBr4, PPh3 / CH2Cl2 / 18 h 2: NaN3 / dimethylformamide / 55 °C 3: 83 percent / H2 / 10percent Pd/C / H2O; ethanol / 5171.5 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 9 p. 3009 - 3016
反应条件
sodium carbonate in tetrahydrofuran T=20°C; 2 h;
参考文献
Zanardi, Franca; Burreddu, Paola; Rassu, Gloria; Auzzas, Luciana; Battistini, Lucia; Curti, Claudio; Sartori, Andrea; Nicastro, Giuseppe; Menchi, Gloria; Cini, Nicoletta; Bottonocetti, Anna; Raspanti, Silvia; Casiraghi, Giovanni
Journal of Medicinal Chemistry, 2008 , vol. 51, # 6 p. 1771 - 1782
