1: 1) 2.3 M n-BuLi / 1) ether, -78 deg C, 5 min, 2) ether, up to room temp. 2: 89 percent / CsF / acetonitrile / Ambient temperature View Scheme

1: 1) 2.3 M n-BuLi / 1) ether, -78 deg C, 5 min, 2) ether, up to room temp. 2: 89 percent / CsF / acetonitrile / Ambient temperature 3: COCl2, DMF / CH2Cl2 / 2 h / Ambient temperature 4: 1) n-BuLi, bipyridyl / 1) THF, -35 -> -5 deg C, 2) THF, -78 deg C, 1 h 5: 98 percent / acetic anhydride / 3 h / Heating 6: ethanol / a) 5 - 15 deg C, 90 min, b) 2 h , room temp. 7: 1) 60percent NaH, 2) 6 M HCl / 1) THF, room temp., 2) reflux, 3 h View Scheme