2-二苯基膦-6-甲基吡啶合成路线 （共 8 条）
反应条件
1: bis-diphenylphosphine With n-butyllithium in tetrahydrofuran; hexane T=20°C; 1 h; 2: 2-chloro-6-methyl-pyridine in tetrahydrofuran; hexane T=20°C; 2 h;
参考文献
Grotjahn, Douglas B.; Lev, Daniel A.
Journal of the American Chemical Society, 2004 , vol. 126, # 39 p. 12232 - 12233
反应条件
methyl-diethoxy-silane; di-p-nitrophenylphosphoric acid in toluene T=110°C; Inert atmosphere; chemoselective reaction;
参考文献
Li, Yuehui; Lu, Liang-Qiu; Das, Shoubhik; Pisiewicz, Sabine; Junge, Kathrin; Beller, Matthias
Journal of the American Chemical Society, 2012 , vol. 134, # 44 p. 18325 - 18329
反应条件
n-butyllithium in diethyl ether; hexane; dichloromethane; water
参考文献
Shell Oil Company
Patent: US5166411 A1, 1992 ;
反应条件
1: diphenylphosphine oxide With cupric triflate; 1,1,3,3-tetramethyldisiloxane in toluene T=100°C; 10 h; Inert atmosphere; 2: 2-bromo-6-methyl-pyridine With caesium carbonate; N-methyl-2-(methylamino)ethylamine in toluene T=20 - 110°C; Inert atmosphere;
参考文献
Li, Yuehui; Das, Shoubhik; Zhou, Shaolin; Junge, Kathrin; Beller, Matthias
Journal of the American Chemical Society, 2012 , vol. 134, # 23 p. 9727 - 9732
反应条件
1: chloro-diphenylphosphine With sodium in 1,4-dioxane 4 h; Heating; 2: 2-chloro-6-methyl-pyridine in 1,4-dioxane Further stages.;
参考文献
Scrivanti; Beghetto; Matteoli
Advanced Synthesis and Catalysis, 2002 , vol. 344, # 5 p. 543 - 547
反应条件
potassium phosphate; [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane T=100°C; Inert atmosphere;
参考文献
Chemistry - A European Journal, , vol. 18, # 31 p. 9622 - 9627
反应条件
6-methylpyridin-2-yl halide in tetrahydrofuran T=20°C; 8 h; Inert atmosphere;
参考文献
Inorganic Chemistry, , vol. 52, # 5 p. 2292 - 2305
反应条件
1: lithium / tetrahydrofuran / 0 - 20 °C / |Inert atmosphere 2: 6-methylpyridin-2-yl halide / tetrahydrofuran / 8 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Inorganic Chemistry, , vol. 52, # 5 p. 2292 - 2305
