(R)-3-(Boc-氨基)异丁酸合成路线 （共 15 条）
反应条件
ruthenium trichloride; sodium periodate in tetrachloromethane; acetonitrile T=25°C; 1 h;
参考文献
Barrow, Russell A.; Hemscheidt, Thomas; Liang, Jian; Paik, Seunguk; Moore, Richard E.; Tius, Marcus A.
Journal of the American Chemical Society, 1995 , vol. 117, # 9 p. 2479 - 2490
反应条件
chromium(VI) oxide; water; periodic acid in acetonitrile T=0°C; 0.5 h;
参考文献
Duursma, Ate; Minnaard, Adriaan J.; Feringa, Ben L.
Journal of the American Chemical Society, 2003 , vol. 125, # 13 p. 3700 - 3701
反应条件
lithium hydroxide in ethanol T=23°C; 0.5 h;
参考文献
Ghosh, Arun K.; Bischoff
European Journal of Organic Chemistry, 2004 , # 10 p. 2131 - 2141
反应条件
1: (2S)-N-{(2R)-2-[(dibenzylamino)methyl]propanoyl}camphorsultam With palladium on activated charcoal in tetrahydrofuran; methanol T=20°C; 2: With lithium hydroxide in tetrahydrofuran; water T=20°C; 3: di-tert-butyl dicarbonate With potassium carbonate in 1,4-dioxane 5 h; Further stages.;
参考文献
Moumne, Roba; Denise, Bernard; Guitot, Karine; Rudler, Henri; Lavielle, Solange; Karoyan, Philippe
European Journal of Organic Chemistry, 2007 , # 12 p. 1912 - 1920
反应条件
sodium periodate; ruthenium trichloride in tetrachloromethane; acetonitrile T=40°C; 2 h;
参考文献
Bower, Justin F.; Jumnah, Roshan; Williams, Andrew C.; Williams, Jonathan M. J.
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 9 p. 1411 - 1420
反应条件
lithium hydroxide; dihydrogen peroxide in tetrahydrofuran T=0°C; 2.5 h;
参考文献
Stoncius, Arvydas; Nahrwold, Markus; Sewald, Norbert
Synthesis, 2005 , # 11 art. no. T12704SS, p. 1829 - 1837
反应条件
[Rh((R,R)-Cy-SMS-Phos)(MeOH)2]BF4; hydrogen in methanol T=20°C; P=750.075 Torr; 0.0666667 h; optical yield given as percent ee;
参考文献
Organic Letters, , vol. 12, # 13 p. 3022 - 3025
反应条件
1: H2 / Pd/C / ethyl acetate 2: aq. LiOH / 0.5 h / 23 °C / Saponification View Scheme
参考文献
Organic letters, , vol. 2, # 11 p. 1573 - 1575
反应条件
1: 91 percent / NaBH4 / ethanol / 1 h / 0 °C 2: H5IO6; H2O; CrO3 / acetonitrile / 0 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 125, # 13 p. 3700 - 3701
反应条件
lithium hydroxide; dihydrogen peroxide in tetrahydrofuran Hydrolysis;
参考文献
Sibi, Mukund P.; Deshpande, Prasad K.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 9 p. 1461 - 1466
