您好，欢迎来到魔法化学网！
合作交流
|
服务时间(9:30-18:00)
百科
百科
▼
百科
资讯
搜索
结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
首页
化合物百科
价格行情
资讯
化工导航
实验室工具
搜索
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
132883-18-2
合成路线
（共 9 条）
5980-33-6
4-甲基伞形酮钠盐
+
132883-18-2
→
反应条件
59361-08-9
4-甲基香豆素基-4,7,8,9-四-氧-乙酰基-α-D-唾液酸甲酯
反应条件
in N,N-dimethyl-formamide 15 h; Inert atmosphere;
参考文献
Zamora, Cristina Y.; D'Alarcao, Marc; Kumar, Krishna
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 11 p. 3406 - 3410
132883-18-2
→
反应条件
73960-72-2
(2R,3R,4S)-3-乙酰氨基-4-乙酰氧基-2-((1R,2R)-1,2,3-三乙酰氧基丙基)-3,4-二氢-2H-吡喃-6-羧酸甲酯
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in benzene Ambient temperature; Yield given;
参考文献
Scheigetz, John; Zamboni, Robert; Bernstein, Michael A.; Roy, Bruno
Organic Preparations and Procedures International, 1995 , vol. 27, # 6 p. 637 - 644
132883-18-2
+
107-18-6
烯丙醇
→
反应条件
73960-72-2
(2R,3R,4S)-3-乙酰氨基-4-乙酰氧基-2-((1R,2R)-1,2,3-三乙酰氧基丙基)-3,4-二氢-2H-吡喃-6-羧酸甲酯
+
73159-07-6
反应条件
silver trifluoromethanesulfonate in dichloromethane T=20°C;
参考文献
Synlett, , # 9 p. 1487 - 1490
132883-18-2
→
反应条件
84380-10-9
4,7,8,9-四-氧-乙酰基-N-神经氨酸甲酯
反应条件
silver carbonate in water; acetone 72 h;
参考文献
Chappell, Mark D.; Halcomb, Randall L.
Tetrahedron, 1997 , vol. 53, # 32 p. 11109 - 11120
132883-18-2
→
反应条件
3063-71-6
胞苷 5'-单磷酸酯 N-乙酰基神经氨酸
反应条件
1: 87 percent / Ag2CO3 / acetone; H2O / 72 h 2: 62 percent / Et3N / acetonitrile / -43 deg C -> room temperature 3: Et3N, t-BuOOH / acetonitrile / 1 h / Ambient temperature 4: iPr2NH, (Ph3P)4Pd / acetonitrile / 0.5 h 5: NaOMe / methanol / 0.5 h 6: aq. NaOH / 0.17 h View Scheme
参考文献
Chappell, Mark D.; Halcomb, Randall L.
Tetrahedron, 1997 , vol. 53, # 32 p. 11109 - 11120
132883-18-2
→
反应条件
139110-80-8
扎那米韦
反应条件
1: 1,8-diazabicyclo<5.4.0>undec-7-ene / benzene / Ambient temperature 2: BF3*Et2O / benzene; methanol / 18 h / Ambient temperature 3: 50percent aq. AcOH / ethyl acetate / Ambient temperature 4: 87 percent / diphenylphosphoryl azide, 1,8-diazabicyclo<5.4.0>undec-7-ene / 23 h / Ambient temperature 5: 78 percent / H2S, pyridine / 1.5 h / Ambient temperature 6: diisopropylethylamine / dimethylformamide / 96 h / Ambient temperature 7: aq. NaOH / methanol / Ambient temperature View Scheme
参考文献
Scheigetz, John; Zamboni, Robert; Bernstein, Michael A.; Roy, Bruno
Organic Preparations and Procedures International, 1995 , vol. 27, # 6 p. 637 - 644
132883-18-2
→
反应条件
130525-58-5
5-乙酰氨基-7,8,9-O-三乙酰基-2,6-脱水-4-叠氮-3,4,5-三脱氧-D-甘油-D-半乳-2-壬烯酸甲酯
反应条件
1: 1,8-diazabicyclo<5.4.0>undec-7-ene / benzene / Ambient temperature 2: BF3*Et2O / benzene; methanol / 18 h / Ambient temperature 3: 50percent aq. AcOH / ethyl acetate / Ambient temperature 4: 87 percent / diphenylphosphoryl azide, 1,8-diazabicyclo<5.4.0>undec-7-ene / 23 h / Ambient temperature View Scheme
参考文献
Scheigetz, John; Zamboni, Robert; Bernstein, Michael A.; Roy, Bruno
Organic Preparations and Procedures International, 1995 , vol. 27, # 6 p. 637 - 644
132883-18-2
→
反应条件
139110-70-6
扎那米韦
反应条件
1: 1,8-diazabicyclo<5.4.0>undec-7-ene / benzene / Ambient temperature 2: BF3*Et2O / benzene; methanol / 18 h / Ambient temperature 3: 50percent aq. AcOH / ethyl acetate / Ambient temperature 4: 87 percent / diphenylphosphoryl azide, 1,8-diazabicyclo<5.4.0>undec-7-ene / 23 h / Ambient temperature 5: 78 percent / H2S, pyridine / 1.5 h / Ambient temperature View Scheme
参考文献
Scheigetz, John; Zamboni, Robert; Bernstein, Michael A.; Roy, Bruno
Organic Preparations and Procedures International, 1995 , vol. 27, # 6 p. 637 - 644
132883-18-2
→
反应条件
78850-37-0
甲基(3aR,4R,7aR)-2-甲基-4-[(1S,2R)-1,2,3-三乙酰氧基丙基]-3a,7a-二氢-4H-吡喃并[3,4-d][1,3]恶唑-6-羧酸酯
反应条件
1: 1,8-diazabicyclo<5.4.0>undec-7-ene / benzene / Ambient temperature 2: BF3*Et2O / benzene; methanol / 18 h / Ambient temperature View Scheme
参考文献
Scheigetz, John; Zamboni, Robert; Bernstein, Michael A.; Roy, Bruno
Organic Preparations and Procedures International, 1995 , vol. 27, # 6 p. 637 - 644
