1: 87 percent / 340 °C / 0.01 - 0.08 Torr 2: 76 percent / MnO2 / CH2Cl2 / 20 °C 3: 88 percent / CF3COOH / 3 h / 0 °C View Scheme

1: 33 percent / 340 °C / 0.1 Torr / flash vacuum pyrolysis 2: 100 percent / 90percent CF3CO2H View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '906717', constants.ctx, '0')">lithium diisopropyl amide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />T=-78 - 0&deg;C;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: NaIO₄ / H₂O; methanol / 0 - 20 &deg;C<br />2: 55 percent / LDA / tetrahydrofuran / -78 - 0 &deg;C<br /> <br /> &nbsp;