1: With bis-triphenylphosphine-palladium(II) chloride in toluene
T=110°C; 3 h; Sealed tube;
2: With hydrogenchloride in tetrahydrofuran
T=20°C; 1 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; PINTO, Donald J.; CORTE, James R.; GILLIGAN, Paul J.; FANG, Tianan; SMITH II, Leon M.; WANG, Yufeng; YANG, Wu; EWING, William R.
Patent: WO2013/22818 A1, 2013 ;
Location in patent: Paragraph 00349 ;
WO 2013/022818 A1