1.1: water; lithium hydroxide hydrate / 1,4-dioxane / 16 h 2.1: 0 °C / Inert atmosphere; Reflux 3.1: diisobutylaluminium hydride; magnesium; lithium chloride; diisobutyl-aluminum chloride / n-heptane; tetrahydrofuran / -10 - 25 °C 3.2: 25 °C View Scheme