potassium hydroxide in methanol T=60°C; 16 h; Inert atmosphere;

<b>Multi-step reaction with 3 steps<br /> </b>1.1: potassium <i>tert</i>-butylate / tetrahydrofuran / 0.17 h / 0 &deg;C / |Inert atmosphere<br />1.2: 2.08 h / |Inert atmosphere<br />2.1: hydrogen; palladium 10 on activated carbon / methanol / 48 h / 1810.07 Torr / |Inert atmosphere<br />3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 &deg;C / |Inert atmosphere<br />3.2: 1 h / 0 - 20 &deg;C / |Inert atmosphere<br /> <br /> &nbsp;