(R)-2,2-二甲基-1,3-二氧戊环-4-丙醇合成路线 （共 5 条）
反应条件
1: With potassium carbonate; ozone in methanol; dichloromethane T=-78°C; 2: With sodium tetrahydroborate in methanol; dichloromethane T=-78 - 20°C;
参考文献
Morin, Matthew D.; Rychnovsky, Scott D.
Organic Letters, 2005 , vol. 7, # 10 p. 2051 - 2053
反应条件
1: CH2Cl2 / 9 h / 20 °C 2: H2 / PtO2 / ethyl acetate / 4 h / 20 °C 3: LiAlH4 / tetrahydrofuran / 3 h / 20 °C View Scheme
参考文献
Sharma; Punna, Sreenivas; Krishna, Palakodety Radha; Chorghade, Mukund S.; Ley, Steven V.
Tetrahedron Asymmetry, 2005 , vol. 16, # 6 p. 1125 - 1133
反应条件
1: 99 percent / H2 / PtO2 / ethyl acetate / 4 h / 20 °C 2: 97 percent / LiAlH4 / tetrahydrofuran / 3 h / 0 - 20 °C View Scheme
参考文献
Sharma; Punna, Sreenivas; Rajendra Prasad; Krishna, Palakodety Radna; Chorghade, Mukund S.; Ley, Steven V.
Tetrahedron Asymmetry, 2005 , vol. 16, # 6 p. 1113 - 1123
反应条件
toluene-4-sulfonic acid T=20°C; 72 h; Title compound not separated from byproducts;
参考文献
Brimble, Margaret A.; Park, Jae H.; Taylor, Carol M.
Tetrahedron, 2003 , vol. 59, # 31 p. 5861 - 5868
反应条件
carbon tetrabromide; triethylamine; triphenylphosphine in dichloromethane T=20°C; Bromination;
参考文献
Yang, Wen-Qian; Kitahara, Takeshi
Tetrahedron, 2000 , vol. 56, # 11 p. 1451 - 1461
