1: With lithium tert-butylate in toluene
1 h;
2: With water in tert-butyl methyl ether; toluene
3: With hydrogenchloride in tert-butyl methyl ether; water
T=20°C; 2 h;
参考文献
Bristol-Myers Squibb Company
Patent: US2007/93414 A1, 2007 ;
Location in patent: Page/Page column 34 ;