2-羟基-2-(2-硝基苯基)乙腈合成路线 （共 18 条）
反应条件
1: 2-nitro-benzaldehyde With sodium hydrogensulfite in water 0.166667 h; 2: potassium cyanide in water T=20°C; 5 h; Cooling with ice;
参考文献
PRESIDENT AND FELLOWS OF HARVARD COLLEGE; CHOREV, Michael; AKTAS, Bertal Huseyin; HALPERIN, Jose A.; WAGNER, Gerhard
Patent: WO2012/6068 A2, 2012 ;
Location in patent: Page/Page column 127-128 ;
反应条件
1: With [C8mim][PF6] T=20°C; 24 h; 2: With hydrogenchloride in tetrahydrofuran
参考文献
Shen, Zhi-Liang; Ji, Shun-Jun
Synthetic Communications, 2009 , vol. 39, # 5 p. 775 - 791
反应条件
in water; acetic acid 1 h; Ambient temperature;
参考文献
Smitskamp-Wilms, E.; Brusse, J.; Gen, A. van der; Scharrenburg, G.J.M. van; Sloothaak, J. B.
Recueil des Travaux Chimiques des Pays-Bas, 1991 , vol. 110, # 5 p. 209 - 215
反应条件
sodium hydrogencarbonate in di-isopropyl ether
参考文献
Van Langen, Luuk M.; Selassa, Rhoderick P.; Van Rantwijk, Fred; Sheldon, Roger A.
Organic Letters, 2005 , vol. 7, # 2 p. 327 - 329
反应条件
in methanol T=4 - 20°C; Substitution; rearrangement; 4.5 h;
参考文献
Corrie, John E. T.; Gradwell, Michael J.; Papageorgiou, George
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 20 p. 2977 - 2982
反应条件
Na2S2O5; water T=35 - 40°C; man versetzt mit KCN in Wasser;
参考文献
Heller; Spielmeyer
Chemische Berichte, 1925 , vol. 58, p. 836
反应条件
hydrogenchloride in tetrahydrofuran
参考文献
Almsick, Andreas van; Buddrus, Joachim; Hoenicke-Schmidt, Petra; Laumen, Kurt; Schneider, Manfred P.
Journal of the Chemical Society, Chemical Communications, 1989 , # 18 p. 1391 - 1393
参考文献
Bell; Henry
Journal of the Chemical Society, 1928 , p. 2226
反应条件
1: alcoholic ammonia 2: alkaline KMnO4 View Scheme
参考文献
Chemische Berichte, , vol. 39, p. 2345
反应条件
1: alcoholic ammonia 2: sodium sulfide View Scheme
参考文献
Heller
Chemische Berichte, 1906 , vol. 39, p. 2345
