1-溴-2,5-二甲氧基-4-甲基苯合成路线 （共 15 条）
反应条件
bromine; acetic acid T=20°C; 2 h;
参考文献
Lanfranchi, Don Antoine; Cesar-Rodo, Elena; Bertrand, Benoit; Huang, Hsin-Hung; Day, Latasha; Johann, Laure; Elhabiri, Mourad; Becker, Katja; Williams, David L.; Davioud-Charvet, Elisabeth
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 31 p. 6375 - 6387
反应条件
borane dimethyl sulfide complex in chlorobenzene T=0 - 130°C; 21 h; Inert atmosphere;
参考文献
Bedford, Robin B.; Bowen, John G.; Weeks, Amanda L.
Tetrahedron, 2013 , vol. 69, # 22 p. 4389 - 4394
反应条件
sodium hydroxide Heating;
参考文献
Scheepers, Brent A.; Klein, Rosalyn; Davies-Coleman, Michael T.
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8243 - 8246
反应条件
1: 61 percent / Me3SiBr; Et4NBF4 / acetonitrile / 20 °C 2: 70 percent / NaOH / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 47 p. 8243 - 8246
反应条件
1: 70 percent / NaOH / Heating 2: 98 percent / AgO; HNO3 / dioxane; H2O / 20 °C 3: 61 percent / Me3SiBr; Et4NBF4 / acetonitrile / 20 °C 4: 70 percent / NaOH / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 47 p. 8243 - 8246
反应条件
1: tin(IV) chloride; bromine / dichloromethane / 20 °C / |Inert atmosphere; |Reflux 2: borane dimethyl sulfide complex / chlorobenzene / 21 h / 0 - 130 °C / |Inert atmosphere View Scheme
参考文献
Tetrahedron, , vol. 69, # 22 p. 4389 - 4394
反应条件
potassium carbonate; acetone
参考文献
Journal of the Chemical Society, , p. 1600,1603
反应条件
pyridine; potassium permanganate
参考文献
Luettringhaus; Gralheer
Justus Liebigs Annalen der Chemie, 1942 , vol. 550, p. 67,83
反应条件
1.1: n-BuLi / tetrahydrofuran; pentane / 0.17 h / -72 °C 1.2: 84 percent / BF3*Et2O / tetrahydrofuran; pentane / 0.42 h 2.1: 90 percent / pyridine / 48 h 3.1: NH3 View Scheme
参考文献
Wagner, Jared M.; McElhinny Jr., Charles J.; Lewin, Anita H.; Carroll, F. Ivy
Tetrahedron Asymmetry, 2003 , vol. 14, # 15 p. 2119 - 2125
反应条件
1: 2-bromo-5-methyl-1,4-dimethoxybenzene With magnesium in tetrahydrofuran 2: 2-bromo-5-methyl-1,4-dimethoxybenzene With bis(triphenylphosphine)palladium(II)-chloride in tetrahydrofuran Heating; Further stages.;
参考文献
Sun, Duoli; Lindeman, Sergey V.; Rathore, Rajendra; Kochi, Jay K.
Journal of the Chemical Society. Perkin Transactions 2, 2001 , # 9 p. 1585 - 1594
