(5-甲基-2-苯基-2H-1,2,3-噻唑-4-基)甲醇合成路线 （共 6 条）
反应条件
1: With triethylamine in toluene T=20 - 85°C; 2: With sodium hydroxide; ethanol; water 1 h; Heating / reflux;
参考文献
US6642234 B1, ;
Page/Page column 50 ;
反应条件
in methanol T=60°C; 2.5 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 19 p. 2555 - 2564
反应条件
dimethylsulfide borane complex in tetrahydrofuran T=20 - 60°C; 4 h;
参考文献
WO2006/13939 A1, ;
Page/Page column 50 ;
WO 2006/013939 A1
反应条件
1: dioxane / 6 h / Heating 2: 78 percent / KOH / methanol / 1) room temperature, 15 min, 2) reflux, 15 min View Scheme
参考文献
Bulletin des Societes Chimiques Belges, , vol. 106, # 11 p. 717 - 728
反应条件
sodium hydroxide; acetyl chloride 1) 20 deg C, 1 d, 2) H2O, reflux, 3 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 106, # 11 p. 717 - 728
反应条件
phosphorus tribromide in dichloromethane T=0°C; 1 h;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: WO2006/13939 A1, 2006 ;
Location in patent: Page/Page column 53 ;
WO 2006/013939 A1
