反应条件
Stage #1: <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '1098229', constants.ctx, '0')">methanol</a>; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />T=20°C; Reflux; <br />Stage #2: <b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '3587310', constants.ctx, '0')">nitric acid</a> <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '1098229', constants.ctx, '0')">methanol</a>; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />3 h; Reflux; <br /> <br />
参考文献
MILLENNIUM PHARMACEUTICALS, INC.; ARMITAGE, Ian; COOPER, Martin, I.; EDDLESTON, Mark, D.; FAIBER, Neil, C.; MCCUBBIN, Quentin, J.; WATT, Stephen, W. Patent: WO2011/103089 A1, 2011 ; Location in patent: Page/Page column 41 ;