1: 71 percent / NaI, Zn, H2O / 1,2-dimethoxy-ethane / 24 h / 90 °C 2: 90 percent / aq. HCl / tetrahydrofuran / 16 h / 22 °C View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 55 percent / NH₃, Li / tetrahydrofuran / 3 h / -50 &deg;C<br />2: 92 percent / pyridine / CHCl₃ / 48 h / 22 &deg;C<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '103233', constants.ctx, '0')">pyridine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a> <br />T=22&deg;C;&nbsp;48&nbsp;h;&nbsp;<br /> &nbsp;