6-甲基-3(2H)-哒嗪酮合成路线 （共 28 条）
反应条件
1: 90 percent / pyridine / 6 h / 0 - 20 °C 2: 62 percent / Et3N / Pd(OAc)2, 1,1'-bis(diphenylphosphino)ferrocene / dimethylformamide / 12 h / 50 °C View Scheme
参考文献
Rohr, Markus; Toussaint, Dominique; Chayer, Said; Mann, Andre; Suffert, Jean; Wermuth, Camille-Georges
Heterocycles, 1996 , vol. 43, # 7 p. 1459 - 1464
反应条件
1: sodium methylate / 130 °C 2: K2cr2O7 View Scheme
参考文献
Journal of the Chemical Society, , p. 2191,2194
反应条件
trichlorophosphate in hexane; water
参考文献
Chemische Berichte, , vol. 34, p. 3263
反应条件
1: K2CO3 / various solvent(s) / 6 h / Heating 2: 1.) 100 percent hydrazine hydrate, 2.) 10 percent aq. HCl / 1.) EtOH, reflux, 4 h, 2.) EtOH, reflux, 2 h View Scheme
参考文献
Yamada, Toshihiro; Nobuhara, Youichi; Shimamura, Hiroshi; Tsukamoto, Yoshitsugu; Yoshihara, Kazuo; et al.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 3 p. 373 - 381
反应条件
1,4-dioxane; potassium hydroxide
参考文献
Aldous; Castle
Arzneimittel Forschung, 1963 , vol. 13, p. 878,879,881
反应条件
copper(II) 7-n-propyl-8-hydroxyquinolinate; potassium carbonate in N,N-dimethyl-formamide
T=140°C; 20 h;
参考文献
Pu, Yu-Ming; Ku, Yi-Yin; Grieme, Tim; Henry, Rodger; Bhatia, Ashok V.
Tetrahedron Letters, 2006 , vol. 47, # 2 p. 149 - 153
反应条件
1: sodium ethylate solution
View Scheme
参考文献
King; McMillan
Journal of the American Chemical Society, 1952 , vol. 74, p. 3222
