1: 2N NaOH / methanol / 15 h / Ambient temperature 2: SOCl2 / toluene / 2.5 h / 95 °C 3: DMAP, Et3N / CH2Cl2 / 22.5 h / Ambient temperature 4: 92 percent / POCl3 / toluene / Ambient temperature 5: molecular sieves / toluene; CH2Cl2 / 94 h / 18 °C 6: 69 percent / NiCl2*6H2O, NaBH4 / tetrahydrofuran / 1 h / Ambient temperature 7: 1.) 2N NaOH, 2.) 2N HCl / 1.) aq. EtOH, 100 deg C, 16 h 8: SOCl2 / 22 h / Ambient temperature 9: Et3N / toluene / 21 h / 110 °C View Scheme