2H-1,2,4-苯并噻二嗪-3(4h)-酮 1,1-二氧化物合成路线 （共 31 条）
反应条件
aluminium trichloride
T=110°C;
参考文献
Rockway, Todd W.; Zhang, Rong; Liu, Dachun; Betebenner, David A.; McDaniel, Keith F.; Pratt, John K.; Beno, David; Montgomery, Debra; Jiang, Wen W.; Masse, Sherie; Kati, Warren M.; Middleton, Tim; Molla, Akhteruzzaman; Maring, Clarence J.; Kempf, Dale J.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 14 p. 3833 - 3838
反应条件
1: 85 percent / propan-2-ol / 4 h / Ambient temperature
2: 90 percent / dimethylformamide / 30 h / Heating
View Scheme
参考文献
Chern; Ho; Wu; Rong; Liu
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 1909 - 1915
反应条件
1: various solvent(s) / -40 - 0 °C
2: AlCl3 / 110 °C
View Scheme
参考文献
Rockway, Todd W.; Zhang, Rong; Liu, Dachun; Betebenner, David A.; McDaniel, Keith F.; Pratt, John K.; Beno, David; Montgomery, Debra; Jiang, Wen W.; Masse, Sherie; Kati, Warren M.; Middleton, Tim; Molla, Akhteruzzaman; Maring, Clarence J.; Kempf, Dale J.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 14 p. 3833 - 3838
反应条件
1: palladium 10 on activated carbon; hydrazine hydrate / ethanol / 1.5 h / Reflux
2: 0.5 h / 180 °C
View Scheme
参考文献
Ismail, Mohamed A.H.; Abou El Ella, Dalal A.; Abouzid, Khaled A.M.; Mahmoud, Amr H.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 7 p. 2455 - 2478
反应条件
1: ammonia
2: palladium 10 on activated carbon; hydrazine hydrate / ethanol / 1.5 h / Reflux
3: 0.5 h / 180 °C
View Scheme
参考文献
Ismail, Mohamed A.H.; Abou El Ella, Dalal A.; Abouzid, Khaled A.M.; Mahmoud, Amr H.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 7 p. 2455 - 2478
反应条件
methylamine
Heating;
参考文献
Raffa,L. et al.
Farmaco, Edizione Scientifica, 1962 , vol. 17, p. 331 - 339
反应条件
1: 78 percent / propan-2-ol / Heating
2: 59 percent / conc. hydrochloric acid / H2O / 24 h / Heating
View Scheme
参考文献
Chern; Ho; Wu; Rong; Liu
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 1909 - 1915
反应条件
1: CHCl3
2: AcOH
3: aq. H2O2, AcOH
View Scheme
参考文献
Kresze,G. et al.
Justus Liebigs Annalen der Chemie, 1968 , vol. 715, p. 223 - 237
反应条件
1: hydrazine hydrate / 1,4-dioxane / 5 h / |Reflux
2: nitric acid; sodium nitrite / water / 2 h / 0 °C
3: toluene / 5 h / |Reflux
View Scheme
参考文献
Ivanova; Borovika; Vozny; Trapencieris; Zalubovskis
Chemistry of Heterocyclic Compounds, 2012 , vol. 48, # 7 p. 1114 - 1116
Khim. Geterotsikl. Soedin., 2012 , vol. 48, # 7 p. 1194 - 1196,3
反应条件
1: nitric acid; sodium nitrite / water / 2 h / 0 °C
2: toluene / 5 h / |Reflux
View Scheme
参考文献
Ivanova; Borovika; Vozny; Trapencieris; Zalubovskis
Chemistry of Heterocyclic Compounds, 2012 , vol. 48, # 7 p. 1114 - 1116
Khim. Geterotsikl. Soedin., 2012 , vol. 48, # 7 p. 1194 - 1196,3
