3,4,5-三甲氧基苯乙腈合成路线 （共 36 条）
反应条件
ethanol; hydrogen sulfide
参考文献
CIBA
Patent: US2505247 , 1946 ;
Full Text Show Details
CIBA
Patent: DE842063 , 1951 ;
DRP/DRBP Org.Chem.
反应条件
2: ethanol View Scheme
参考文献
CIBA
Patent: US2161938 , 1938 ;
反应条件
sulfuric acid; palladium; acetic acid Hydrogenation;
参考文献
Short,J.H. et al.
Tetrahedron, 1973 , vol. 29, p. 1931 - 1939
反应条件
hydroxylamine hydrochloride; sodium hydroxide in ethanol; water
5 h; Reflux;
参考文献
Tsyganov, Dmitry V.; Khrustalev, Victor N.; Konyushkin, Leonid D.; Raihstat, Mikhail M.; Firgang, Sergei I.; Semenov, Roman V.; Kiselyov, Alex S.; Semenova, Marina N.; Semenov, Victor V.
European Journal of Medicinal Chemistry, 2014 , vol. 73, p. 112 - 125
参考文献
Baker; Robinson
Journal of the Chemical Society, 1929 , p. 159
Journal of the Chemical Society, 1926 , p. 2718
反应条件
1: 91 percent / gaseous HCl / Ambient temperature
2: tetrahydrofuran / Ambient temperature
3: CH3SO3H / acetic acid / Ambient temperature
4: 25percent NaOH
View Scheme
参考文献
Robey; Copley-Merriman; Phelps
Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 3 p. 779 - 783
