1: diisobutylaluminium hydride / dichloromethane; toluene / 3 h / -78 °C 2: triethylamine / 12 h / 20 °C 3: methanesulfonyl chloride; triethylamine / dichloromethane / 0 - 20 °C 4: sodium tetrahydroborate / ethanol / 0 - 20 °C 5: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C 6: triethylamine / tetrahydrofuran / 0 - 20 °C 7: trifluoroacetic acid / 1,2-dichloro-ethane / 8 h / 50 °C 8: triethylamine / dichloromethane / 0 - 20 °C 9: palladium diacetate; p-benozquinone / acetonitrile / 0 - 50 °C 10: L-Selectridereg; / tetrahydrofuran / -78 - 20 °C 11: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 50 °C View Scheme

1: diisobutylaluminium hydride / dichloromethane; toluene / 3 h / -78 °C 2: triethylamine / 12 h / 20 °C 3: methanesulfonyl chloride; triethylamine / dichloromethane / 0 - 20 °C 4: sodium tetrahydroborate / ethanol / 0 - 20 °C 5: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C 6: triethylamine / tetrahydrofuran / 0 - 20 °C 7: trifluoroacetic acid / 1,2-dichloro-ethane / 8 h / 50 °C 8: L-Selectridereg; / tetrahydrofuran / -78 - 20 °C 9: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 45 °C View Scheme