1: chloro-trimethyl-silane / tetrahydrofuran / 2 h / -40 °C 2: palladium 10 on activated carbon; hydrogen / ethanol 3: 4-(N,N-dimethlyamino)pyridine / pyridine / 0 - 20 °C 4: ammonium cerium (IV) nitrate / water; acetonitrile / 20 °C 5: 4-(N,N-dimethlyamino)pyridine; triethylamine / tetrahydrofuran / 20 °C / Reflux 6: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 20 °C 7: N,N,N',N',N'',N''-hexamethylphosphoric triamide; lithium diisopropyl amide / tetrahydrofuran; hexane / 4 h / -78 °C 8: trifluoroacetic acid / dichloromethane / 4 - 20 °C 9: water; sodium hydroxide / 64 h / 4 °C 10: bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine / dichloromethane / 2 h View Scheme

1: chloro-trimethyl-silane / tetrahydrofuran / 2 h / -40 °C 2: palladium 10 on activated carbon; hydrogen / ethanol 3: 4-(N,N-dimethlyamino)pyridine / pyridine / 0 - 20 °C 4: ammonium cerium (IV) nitrate / water; acetonitrile / 20 °C 5: 4-(N,N-dimethlyamino)pyridine; triethylamine / tetrahydrofuran / 20 °C / Reflux 6: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 20 °C 7: N,N,N',N',N'',N''-hexamethylphosphoric triamide; lithium diisopropyl amide / tetrahydrofuran; hexane / 4 h / -78 °C 8: trifluoroacetic acid / dichloromethane / 4 - 20 °C 9: water; sodium hydroxide / 64 h / 4 °C View Scheme