1: 98 percent / pyridine, 4-N,N-dimethylaminopyridine / CH2Cl2 / 1.) 0 deg C, 2.) 3 h, room temperature 2: 76.8 percent / NaH / dimethylsulfoxide / 0.5 h / Ambient temperature 3: 82.2 percent / Et4NOTs, HOAc, t-BuOH / 1.) anodic oxidation (3.3 mA cm-1), room temperature, 2.) room temperature, 1 d View Scheme

1: 98 percent / pyridine, 4-N,N-dimethylaminopyridine / CH2Cl2 / 1.) 0 deg C, 2.) 3 h, room temperature 2: 76.8 percent / NaH / dimethylsulfoxide / 0.5 h / Ambient temperature 3: 82.2 percent / Et4NOTs, HOAc, t-BuOH / 1.) anodic oxidation (3.3 mA cm-1), room temperature, 2.) room temperature, 1 d 4: K2CO3 / dimethylformamide / 75 - 80 °C 5: 2N aq. NaOH / 3 h / Heating 6: 83.8 percent / N-methyl-2-pyrrolidinone / 20 h / 100 °C View Scheme