in water

1: thionyl chloride / N,N-dimethyl-formamide / 1.5 h / 80 °C 2: ammonium hydroxide / chloroform / 0.5 h / 5 °C 3: trichlorophosphate / 2 h / 80 °C View Scheme

1: ammonium hydroxide / chloroform / 0.5 h / 5 °C 2: trichlorophosphate / 2 h / 80 °C View Scheme

1.1: n-butyllithium / diethyl ether; hexane / 0.03 h / -78 °C / |Inert atmosphere 1.2: -78 - 20 °C / |Inert atmosphere 1.3: |Inert atmosphere 2.1: thionyl chloride / N,N-dimethyl-formamide / 1.5 h / 80 °C 3.1: ammonium hydroxide / chloroform / 0.5 h / 5 °C 4.1: trichlorophosphate / 2 h / 80 °C View Scheme