(3S)-3-[[(9H-芴-9-基甲氧基)羰基]氨基]-4-羟基-丁酸叔丁酯合成路线 (共 5 条)
反应条件
1: With 4-methyl-morpholine in ethylene glycol dimethyl ether T=-15°C; 1 h; 2: With sodium tetrahydroborate in ethylene glycol dimethyl ether; water T=-15°C; Further stages.;
参考文献
Boeijen; Van Ameijde; Liskamp
Journal of Organic Chemistry, 2001 , vol. 66, # 25 p. 8454 - 8462
反应条件
sodium tetrahydroborate in tetrahydrofuran T=20°C; 0.5 h;
参考文献
Papavassilopoulou, Eleni; Christofis, Petros; Terzoglou, Despina; Moutevelis-Minakakis, Panagiota
Tetrahedron Letters, 2007 , vol. 48, # 47 p. 8323 - 8325
反应条件
sodium tetrahydroborate in ethylene glycol dimethyl ether; water T=20°C; 1 h;
参考文献
Chen, Jack J.; Aduda, Vince
Synthetic Communications, 2007 , vol. 37, # 20 p. 3493 - 3499
反应条件
sodium borohydride in tetrahydrofuran; methanol; ammonium chloride
参考文献
US6552168 B1, ;
US 6552168 B1
反应条件
sodium tetrahydroborate in methanol T=20°C;
参考文献
Journal of Chemical Research, , # 12 p. 683 - 685