(R)-(+)-3-甲基环己酮合成路线 （共 64 条）
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene 4 h; Heating;
参考文献
Chemistry Letters, , # 9 p. 1637 - 1640
反应条件
1: 92 percent / TiBr2(i-PrO2)2, (4R,5R)-α,α,α',α'-tetraphenyl-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol, mol. sieves 4A / CH2Cl2 / 24 h / -78 °C 2: 95 percent / HCl / tetrahydrofuran / 2 h / Ambient temperature 3: H2, 10percent Pd-C / tetrahydrofuran; ethanol 4: n-Bu3SnH, AIBN / benzene / 4 h / Heating View Scheme
参考文献
Chemistry Letters, , # 9 p. 1637 - 1640
反应条件
1: H2, 10percent Pd-C / tetrahydrofuran; ethanol 2: n-Bu3SnH, AIBN / benzene / 4 h / Heating View Scheme
参考文献
Chemistry Letters, , # 9 p. 1637 - 1640
反应条件
1: 95 percent / HCl / tetrahydrofuran / 2 h / Ambient temperature 2: H2, 10percent Pd-C / tetrahydrofuran; ethanol 3: n-Bu3SnH, AIBN / benzene / 4 h / Heating View Scheme
参考文献
Chemistry Letters, , # 9 p. 1637 - 1640
反应条件
1: 1.) n-BuLi / 1.) THF, -78 degC, 90 min; 2.) THF, -78 degC, 15 min 2: 75 percent / CuSO4 / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 40, # 8 p. 1401 - 1408
反应条件
1: 75 percent / CuSO4 / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 40, # 8 p. 1401 - 1408
反应条件
acetic anhydride Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 25, # 51 p. 5911 - 5912
反应条件
aluminum amalgam; 18-crown-6 ether 1.) DME, -64 deg C, 1.5 h, 2.) THF, H2O, -15 deg C, then warmed to room temp.; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 25, # 4 p. 379 - 382
反应条件
aluminum amalgam 1.) THF, -78 degC, 1 h, then 0 degC, 2 h; 2.) THF/H2O; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 40, # 8 p. 1401 - 1408
反应条件
aluminum amalgam 1.) THF, -78 degC, 1 h, then 0 degC, 2 h; 2.) THF/H2O; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 40, # 8 p. 1401 - 1408
