三环[5,2,1,0(2,6)]癸-8-酮合成路线 （共 14 条）
反应条件
3-mercapto-propionic acid T=100°C; 12 h; Amberlyst.(R).-15 ion exchange resin; Product distribution / selectivity;
参考文献
Kapila, Debjani; Krishnamurti, Ramesh; Lens, Jan-Pleun; Kishan, Gurram; Kukalyekar, Nileshkumar; Thampi, Jegadeesh; Hasyagar, Umesh Krishna; Rai, Vinod Kumar; Shyadligeri, Ashok S.; Arakali, Radhakrishna Sreenivasarao; Nesakumar, Edward J.; Kumbhar, Pramod
Patent: US2005/137428 A1, 2005 ;
Location in patent: Page/Page column 5-6 ;
反应条件
sodium tetrahydroborate; trifluorormethanesulfonic acid in 1,2,2-trifluoro-trichloroethane T=-78 - 20°C; 18 h;
参考文献
Olah, George A.; Wu, An-hsiang; Farooq, Omar; Prakash, G. K. Surya
Journal of Organic Chemistry, 1989 , vol. 54, # 6 p. 1450 - 1451
反应条件
ammonium chloride T=60°C; 10 h;
参考文献
Ma, Zhenkun; Huang, Qingtao; Bobbitt, James M.
Journal of Organic Chemistry, 1993 , vol. 58, # 18 p. 4837 - 4843
反应条件
thionyl chloride
1.) Et2O, -78 deg C, 30 min, 2.) a) -78 deg C, 5 min, b) RT, 30 min; Yield given. Multistep reaction;
参考文献
Olah, George A.; Wu, An-hsiang; Farooq, Omar
Journal of Organic Chemistry, 1989 , vol. 54, # 6 p. 1375 - 1378
