3,5-二甲氧基苯基乙腈合成路线 （共 28 条）
反应条件
1: 86 percent / PBr3 / CH2Cl2 / 1 h / 20 °C 2: 83 percent / dimethylformamide / 1 h View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 4-5 p. 583 - 594
反应条件
in dimethyl sulfoxide 4 h;
参考文献
Bianchi; Alesso; Moltrasio Iglesias
Organic Preparations and Procedures International, 1996 , vol. 28, # 2 p. 230 - 234
反应条件
diethylene glycol monoethyl ether; sodium amide in ethylene glycol dimethyl ether 1.) 45 deg C, 2 h, 2.) -10 deg C, 2 h, 3.) -20 deg C, 18 h;
参考文献
Carre, M. C.; Ezzinadi, A. S.; Zouaoui, M. A.; Geoffroy, P.; Caubere, P.
Synthetic Communications, 1989 , vol. 19, # 19 p. 3323 - 3330
反应条件
1: 93 percent / BH3*THF / tetrahydrofuran / 12 h 2: 70 percent / methanesulfonyl chloride; triethylamine 3: 1-methyl-pyrrolidin-2-one / 5 h View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 19 p. 5942 - 5943
反应条件
in dimethyl sulfoxide T=35 - 40°C; 1.5 h;
参考文献
Jamie, Joanne F.; Rickards, Rodney W.
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 24 p. 3613 - 3621
反应条件
1.1: LiAlH4 / tetrahydrofuran / 3 h / 20 °C 1.2: 97 percent / Na/K tartrate / tetrahydrofuran / 1 h / 20 °C 2.1: 86 percent / PBr3 / CH2Cl2 / 1 h / 20 °C 3.1: 83 percent / dimethylformamide / 1 h View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 4-5 p. 583 - 594
反应条件
1: LiAlH4 / diethyl ether 2: SOCl2 / diethyl ether 3: ethanol View Scheme
参考文献
Archiv der Pharmazie, , vol. 305, # 2 p. 124 - 134
参考文献
Tetrahedron, , vol. 18, p. 1519 - 1526
反应条件
ammonia; sodium; iron(III) chloride
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 1032 - 1043
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Kametani,T. et al.
Journal of the Chemical Society [Section] C: Organic, 1971 , p. 1032 - 1043
