1-(4-氯苯基)-4-甲醇基-1H-1,2,3-三唑合成路线 (共 5 条)
反应条件
copper(II) sulfate; sodium L-ascorbate in water; tert-butyl alcohol Huisgen Cycloaddition;
参考文献
Medicinal Chemistry, , vol. 9, # 8 p. 1085 - 1090
反应条件
sodium tetrahydroborate in methanol 2 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 27, # 7 p. 2021 - 2027
反应条件
1.1: hydrogenchloride; sodium nitrite / water / 0.5 h / 0 - 5 °C 1.2: 0 - 20 °C 2.1: CuSO4‵5H2O; sodium L-ascorbate / water; tert-butyl alcohol / 20 °C / Darkness View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 17 p. 5988 - 5999
反应条件
1: 83 percent / toluene / Heating 2: 91 percent / NaBH4 / methanol / 2 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 27, # 7 p. 2021 - 2027
反应条件
manganese(IV) oxide in dichloromethane Ambient temperature;
参考文献
Journal of Heterocyclic Chemistry, , vol. 27, # 7 p. 2021 - 2027