1-氯-3-(氯苯基甲基)苯合成路线 （共 7 条）
反应条件
thionyl chloride in dichloromethane T=0°C; 2 h;
参考文献
Denegri, Bernard; Streiter, Andre; Juric, Sandra; Ofial, Armin R.; Kronja, Olga; Mayr, Herbert
Chemistry - A European Journal, 2006 , vol. 12, # 6 p. 1648 - 1656
反应条件
1: 27.5 g / NaBH4 / ethanol / 12 h / 20 °C 2: 86 percent / SOCl2 / CH2Cl2 / 2 h / 0 °C View Scheme
参考文献
Kline, Richard H.; Izenwasser, Sari; Katz, Jonathan L.; Joseph, David B.; Bowen, Wayne D.; Newman, Amy Hauck
Journal of Medicinal Chemistry, 1997 , vol. 40, # 6 p. 851 - 857
反应条件
2: NaBH4 / propan-2-ol 3: HCl, Drierite / CH2Cl2 View Scheme
参考文献
Nishida,S.
Journal of Organic Chemistry, 1967 , vol. 32, p. 2692 - 2695
反应条件
2: NaBH4 / propan-2-ol 3: HCl, Drierite / CH2Cl2 View Scheme
参考文献
Nishida,S.
Journal of Organic Chemistry, 1967 , vol. 32, p. 2692 - 2695
反应条件
1.1: Mg / tetrahydrofuran / Heating 1.2: tetrahydrofuran / 2 h / 20 °C 2.1: 27.5 g / NaBH4 / ethanol / 12 h / 20 °C 3.1: 86 percent / SOCl2 / CH2Cl2 / 2 h / 0 °C View Scheme
参考文献
Denegri, Bernard; Streiter, Andre; Juric, Sandra; Ofial, Armin R.; Kronja, Olga; Mayr, Herbert
Chemistry - A European Journal, 2006 , vol. 12, # 6 p. 1648 - 1656
反应条件
1.1: Mg / tetrahydrofuran / Heating 1.2: tetrahydrofuran / 2 h / 20 °C 2.1: 27.5 g / NaBH4 / ethanol / 12 h / 20 °C 3.1: 86 percent / SOCl2 / CH2Cl2 / 2 h / 0 °C View Scheme
参考文献
Denegri, Bernard; Streiter, Andre; Juric, Sandra; Ofial, Armin R.; Kronja, Olga; Mayr, Herbert
Chemistry - A European Journal, 2006 , vol. 12, # 6 p. 1648 - 1656
反应条件
sodium tetrahydroborate in diethylene glycol dimethyl ether; water T=45°C; 24 h; var. amount of NaBH4, var. time; Rate constant;
参考文献
Journal of the Chinese Chemical Society, , vol. 44, # 3 p. 249 - 252
