2-氯-3-甲基-4-吡啶羧酸合成路线 （共 2 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 18.5 h; Inert atmosphere;
参考文献
EPIZYME, INC.; EISAI CO., LTD.; KUNTZ, Kevin, Wayne; CHESWORTH, Richard; DUNCAN, Kenneth, William; KEILHACK, Heike; WARHOLIC, Natalie; KLAUS, Christine; ZHENG, Wanjun
Patent: WO2012/142513 A1, 2012 ;
Location in patent: Page/Page column 428 ;
WO 2012/142513 A1
反应条件
1: With pyridine; methanesulfonyl chloride T=0°C; 2: With ammonia T=20°C; 1 h;
参考文献
JANSSEN PHARMACEUTICA NV
Patent: WO2009/135944 A1, 2009 ;
Location in patent: Page/Page column 23 ;
