1: 51 percent / NaN(SiMe3)2 / tetrahydrofuran / 1.) room temperature, 2.) -90 deg C 2: H+ / tetrahydrofuran 3: 76 percent / NaN(SiMe3)2 / tetrahydrofuran / -80 °C View Scheme

1: (3-(methoxycarbonyl)propyl)triphenylphosphonium bromide With sodium hexamethyldisilazane in tetrahydrofuran T=-20°C; 0.333333 h; Inert atmosphere; 2: isobutyraldehyde in tetrahydrofuran T=-78 - 20°C; Inert atmosphere;

1: 1.) potassium 2-methyl-2-butanolate / 1.) hexamethylphosphoric triamide, 0 deg C, 15 min, 2.) benzene, 20 deg C, 1 h 2: 87 percent / H2 / 10percent Pd/C / ethyl acetate View Scheme

potassium tert-butylate in tetrahydrofuran