(3,5-二氯苯基)(苯基)甲酮合成路线 (共 5 条)
反应条件
1: 1-bromo-3,5-dichloro-benzene With magnesium in tetrahydrofuran T=20°C; Reflux; 2: benzonitrile in tetrahydrofuran 48 h; Reflux; 3: With hydrogenchloride; water in tetrahydrofuran 4 h;
参考文献
TRANSITIONS OPTICAL, INC.
Patent: WO2012/82999 A1, 2012 ;
Location in patent: Page/Page column 39 ;
反应条件
1: 3,5-dichlorophenylzinc bromide With CCl2CuLi2N in tetrahydrofuran T=-20 - 0°C; Negishi coupling reaction; Inert atmosphere; 2: benzoyl chloride in tetrahydrofuran T=-20 - 20°C; Negishi coupling reaction; 2 h; Inert atmosphere;
参考文献
Jin, Meng-Yi; Yoshikai, Naohiko
Journal of Organic Chemistry, 2011 , vol. 76, # 7 p. 1972 - 1978
反应条件
durch Eliminierung der Aminogruppe;
参考文献
Waters
Journal of the Chemical Society, 1929 , p. 2108
参考文献
Lock; Roediger
Chemische Berichte, 1939 , vol. 72, p. 861,868
参考文献
Lock; Roediger
Chemische Berichte, 1939 , vol. 72, p. 861,868