1-(4-氨基苯基)-3-(环己基甲基)-3-氮杂双环[3.1.0]己烷-2,4-二酮合成路线 （共 4 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
参考文献
Stanek; Alder; Bellus; Bhatnagar; Hausler; Schieweck
Journal of Medicinal Chemistry, 1991 , vol. 34, # 4 p. 1329 - 1334
反应条件
1: 1.) xylene, reflux, 5 h, 2.) xylene, reflux, 15 h 2: 60 percent / concd. sulfuric acid, nitric acid / 2 h / 10 °C 3: 84 percent / H2 / 5percent Pd/C / ethyl acetate View Scheme
参考文献
Stanek; Alder; Bellus; Bhatnagar; Hausler; Schieweck
Journal of Medicinal Chemistry, 1991 , vol. 34, # 4 p. 1329 - 1334
反应条件
1: 60 percent / concd. sulfuric acid, nitric acid / 2 h / 10 °C 2: 84 percent / H2 / 5percent Pd/C / ethyl acetate View Scheme
参考文献
Stanek; Alder; Bellus; Bhatnagar; Hausler; Schieweck
Journal of Medicinal Chemistry, 1991 , vol. 34, # 4 p. 1329 - 1334
反应条件
1: 1.) xylene, reflux, 5 h, 2.) xylene, reflux, 15 h 2: 60 percent / concd. sulfuric acid, nitric acid / 2 h / 10 °C 3: 84 percent / H2 / 5percent Pd/C / ethyl acetate View Scheme
参考文献
Stanek; Alder; Bellus; Bhatnagar; Hausler; Schieweck
Journal of Medicinal Chemistry, 1991 , vol. 34, # 4 p. 1329 - 1334
