3-苯基-2-(4,4,4-三氟-3-氧代-1-丁烯氨基)-丙酸合成路线 （共 3 条）
反应条件
sodium hydroxide in dichloromethane T=20°C; 0.25 h;
参考文献
Zanatta, Nilo; Squizani, Adriana M. C.; Fantinel, Leonardo; Nachtigall, Fabiane M.; Bonacorso, Helio G.; Martins, Marcos A. P.
Synthesis, 2002 , # 16 p. 2409 - 2415
反应条件
hydrogenchloride in methanol T=70°C; 20 h;
参考文献
Zanatta, Nilo; Squizani, Adriana M. C.; Fantinel, Leonardo; Nachtigall, Fabiane M.; Bonacorso, Helio G.; Martins, Marcos A. P.
Synthesis, 2002 , # 16 p. 2409 - 2415
反应条件
1: 82 percent / triethylamine, 1,3-dicyclohexylcarbodiimide / CH2Cl2 / 1 h / 0 °C
2: 3 N aq. HCl / dioxane / 10 h / Ambient temperature
View Scheme
参考文献
Gorbunova; Gerus; Galushko; Kukhar
Synthesis, 1991 , # 3 p. 207 - 209
