7-氯-4,4-二甲基-3,4-二氢-1H-喹啉-2-酮合成路线 （共 3 条）
反应条件
AlCl3, aluminium chloride in 1,2-dichloro-benzene T=20°C; Friedel-Crafts Alkylation; 4 h; Inert atmosphere;
参考文献
Lee, Eun; Han, Seulaa; Jin, Guo Hua; Lee, Hwa Jin; Kim, Woo-Young; Ryu, Jae-Ha; Jeon, Raok
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3976 - 3978
反应条件
1.1: triethylamine / tetrahydrofuran / 0.5 h / 20 °C / |Inert atmosphere 1.2: 16 h / 0 - 20 °C / |Inert atmosphere 2.1: AlCl3, aluminium chloride / 1,2-dichloro-benzene / 4 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Lee, Eun; Han, Seulaa; Jin, Guo Hua; Lee, Hwa Jin; Kim, Woo-Young; Ryu, Jae-Ha; Jeon, Raok
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3976 - 3978
反应条件
1.1: triethylamine / tetrahydrofuran / 0.5 h / 20 °C / |Inert atmosphere 1.2: 16 h / 0 - 20 °C / |Inert atmosphere 2.1: AlCl3, aluminium chloride / 1,2-dichloro-benzene / 4 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Lee, Eun; Han, Seulaa; Jin, Guo Hua; Lee, Hwa Jin; Kim, Woo-Young; Ryu, Jae-Ha; Jeon, Raok
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3976 - 3978
