3-氯-2,2-二甲基-1-丙醇合成路线 （共 7 条）
反应条件
4-(N,N-dimethlyamino)pyridine; trichlorophosphate in dichloromethane T=20°C;
参考文献
Tetrahedron Letters, , vol. 43, # 1 p. 15 - 17
反应条件
pyridine; dichlorotriphenylphosphorane in chloroform 12 h; Ambient temperature;
参考文献
Acta Chemica Scandinavica, , vol. 45, # 1 p. 82 - 91
反应条件
potassium hydroxide in ethylene glycol T=60°C; 1 h;
参考文献
Dale, Johannes; Fredriksen, Siw B.
Acta Chemica Scandinavica, 1991 , vol. 45, # 1 p. 82 - 91
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide in dichloromethane T=-78°C; 0.5 h; Inert atmosphere; 2: With triethylamine in dichloromethane T=-78 - 20°C; Inert atmosphere;
参考文献
Trost, Barry M.; Bartlett, Mark J.; Weiss, Andrew H.; Vonwangelin, Axel Jacobi; Chan, Vincent S.
Chemistry - A European Journal, 2012 , vol. 18, # 51 p. 16498 - 16509
反应条件
1: 80 percent / pyridinium chlorochromate
2: 30 percent / dimethylsulfoxide / 2 h / 58 °C
3: 71 percent / chloroplatinic acid hexahydrate / ethanol / 1.25 h / 65 - 75 °C
View Scheme
参考文献
Wilt,J.W.; Aznavoorian,P.M.
Journal of Organic Chemistry, 1978 , vol. 43, # 6 p. 1285 - 1286
反应条件
1,1,1,3,3,3-hexamethyl-disilazane; chloro-trimethyl-silane in argon
参考文献
FMC Corporation
Patent: US5543540 A1, 1996 ;
反应条件
1,1,1,3,3,3-hexamethyl-disilazane in cyclohexane; argon
参考文献
FMC Corporation
Patent: US5403946 A1, 1995 ;
