palladium diacetate; N,N-dimethyl-formamide; potassium hydroxide T=145°C; 6 h; Inert atmosphere; optical yield given as percent destereoselective reaction;

copper in quinoline T=220°C; 3 h;

1: 4-methoxybenzyl-triphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=-78 - 20°C; 1.5 h; 2: 3,4,5-trimethoxy-benzaldehyde in tetrahydrofuran; hexane T=-78 - 20°C; Wittig reaction; 19 h;

1,2-dibromo-1,1,2,2-tetrafluoroethane in tert-butyl alcohol Ramberg-Baecklund reaction; 12 h; Heating;

copper(l) iodide; 1,10-phenanthroline T=180 - 190°C; Microwave irradiationInert atmosphereGreen chemistry;

sodium hydride in benzene 16 h; Ambient temperature;

1: 2-methoxy-1,3-butadiene; triphenyl(prop-2-ynyl)phosphonium bromide With zinc(II) iodide; zinc; CoBr2(1,2-bis(diphenylphosphino)ethane) in dichloromethane T=20°C; Diels-Alder reaction; 0.5 h; 2: 3,4,5-trimethoxy-benzaldehyde With potassium tert-butylate in dichloromethane T=20°C; 1 h; 3: With 2,3-dicyano-5,6-dichloro-p-benzoquinone in benzene T=20°C; 1 h; Further stages.;

1: toluene / 6 h / Heating 2: 0.8 g / n-butyllithium / hexane; tetrahydrofuran / 16 h / -78 °C View Scheme

quinoline; copper T=200°C; 2 h;

1: (4-methoxybenzyl)triphenylphosphonium chloride in tetrahydrofuran; hexane T=-78°C; 1 h; Inert atmosphere; 2: N-(3,4,5-trimethoxybenzylidene)-p-toluenesulfonamide in tetrahydrofuran; hexane T=-78 - 20°C; 12 h; Inert atmosphere; optical yield given as percent destereoselective reaction;