5'-O-[(二异丙基氨基)-(2-氰基乙氧基)氧磷基]-3'-O-(4,4'-二甲氧基三苯甲基)胸苷合成路线 （共 7 条）
反应条件
1H-tetrazole in acetonitrile
参考文献
Wagner, Thomas; Pfleiderer, Wolfgang
Helvetica Chimica Acta, 2000 , vol. 83, # 8 p. 2023 - 2035
反应条件
1: 94 percent / pyridine / CH2Cl2 / 2 h / 60 °C 2: 90 percent / DBU / acetonitrile / 2 h / 20 °C 3: 73 percent / 1H-tetrazole / acetonitrile / 1 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 83, # 8 p. 2023 - 2035
反应条件
1: 94 percent / pyridine / 2 h / 60 °C 2: 96 percent / (Bu4N)F*H2O; AcOH / tetrahydrofuran / 20 °C 3: 73 percent / 1H-tetrazole / acetonitrile / 1 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 83, # 8 p. 2023 - 2035
反应条件
1: 94 percent / pyridine / CH2Cl2 / 2 h / 60 °C 2: 90 percent / DBU / acetonitrile / 2 h / 20 °C 3: 73 percent / 1H-tetrazole / acetonitrile / 1 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 83, # 8 p. 2023 - 2035
反应条件
1: 96 percent / (Bu4N)F*H2O; AcOH / tetrahydrofuran / 20 °C 2: 73 percent / 1H-tetrazole / acetonitrile / 1 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 83, # 8 p. 2023 - 2035
反应条件
1: 90 percent / DBU / acetonitrile / 2 h / 20 °C 2: 73 percent / 1H-tetrazole / acetonitrile / 1 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 83, # 8 p. 2023 - 2035
反应条件
1: 86 percent / 1H-imidazole / dimethylformamide / 2 h / 20 °C 2: 94 percent / pyridine / 2 h / 60 °C 3: 96 percent / (Bu4N)F*H2O; AcOH / tetrahydrofuran / 20 °C 4: 73 percent / 1H-tetrazole / acetonitrile / 1 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 83, # 8 p. 2023 - 2035
